Here is a good review article from the “yellow journal” on metastasis to the spine!
Rose, P., Buchowski, J. (2011). Metastatic Disease in the Thoracic and Lumbar Spine American Academy of Orthopaedic Surgeon 19(1), 37-48. https://dx.doi.org/10.5435/00124635-201101000-00005
Download PDF from the rochester.edu website
As a complement to this article, I found a good video lecture on this topic by Dr. Laurence Rhinnes from MD Anderson.
Amazing animation that demonstrated the biological and clinical effects of bone metastases on the skeleton.
The animation is by Amgen, a biotechnology company.
Please visit their Youtube channel Amgen for more videos.
The spine is one of the most common site for metastasis. Effective management of spinal metastasis requires a logical and systematic approach.
Dr. Laurence D. Rhines, MD is the Professor of Neurosurgery at The University of Texas MD Anderson Cancer Center, Houston, USA.
In his excellent and lucid talk given at the Seattle Science Foundation, Dr. Rhines puts forth four questions to ask ourselves when dealing with spinal metastasis.
1) Is the patient medically fit to undergo a procedure?
2) What is the clinical presentation?
3) What is the pathology (histology)?
4) Do you have a feasible surgical plan?
For more details, please watch the following lecture.
Metastatic lesions account for majority spinal tumors. Primary spinal malignancies are rare, however, surgery in these tumours can be curative if performed with an en bloc technique. Intralesional excision of primary spinal tumor such as chordoma is associated with a 100% recurrence rate. Hence, it is important to know the histological diagnosis before embarking on surgical treatment for any spinal tumor. A surgeon will get only one chance to offer curative surgery in primary spinal malignancy and biopsy is extremely important to different such malignancies from the more common metastatic lesions.
Following is an excellent talk from the Seattle Science Foundation by Dr. Ehud Mendel, Professor of Neurosurgery at Ohio State University, Columbus, OH, on considerations for En Bloc resection for primary spinal tumors.